PERSEPSI PASIEN HIPERTENSI TERHADAP KEAMANAN DAN EFEKTIFITAS OBAT TRADISIONAL UNTUK HIPERTENSI DI KABUPATEN BANYUMAS

Aulia Rahman; Dyah Aryani  Perwitasari; Kintoko Kintoko; Suwijiyo  Pramono

Penulis

Aulia Rahman UNIVERSITAS PERADABAN
Dyah Aryani Perwitasari Universitas Peradaban
Kintoko Kintoko Universitas Ahmad Dahlan Yogyakarta
Suwijiyo Pramono Universitas Gadjah Mada Yogyakarta

Abstrak

Hypertension is the biggest risk factor for cardiovascular disease which is the first caused of death in the world. Besides lifestyle modification and pharmacological therapy, hypertension can also be treated using traditional medicine. The use of traditional medicine can be influenced by characteristics and perceptions. The purpose of this study was to determine the patient's perception of traditional medicine for hypertension in Banyumas Regency. The research was conducted in April 2019, the subjects were hypertensive patients who become member of PROLANIS in Banyumas Regency. The research design used a cross-sectional study with a purposive random sampling. Perception was measured using a questionnaire with a Likert scale from strongly disagree to strongly agree (scale 1-5) then converted into a percent index score. There were 340 respondents who participated in this study. The majority of respondents were women (56.8%) aged 45-60 years old (52.4%), with secondary education (55.3%), working (85%) and having moderate income (52.6%) . Respondents have a good perception of the safety and effectiveness of traditional medicines for hypertension with an average percent index score of 68.53% for safety and an 67.38% for effectiveness

Referensi

Al-Ramahi, R. et al. (2015) Evaluation of potential drug- herb interactions among a group of Palestinian patients with chronic diseases, BMC Complementary and Alternative Medicine. BioMed Central, 15(1), hal. 221.

Asdaq, S. M. B. dan Inamdar, M. N. (2009) Pharmacodynamic interaction of captopril with garlic in isoproterenol-induced myocardial damage in rat, Phytotherapy Research. John Wiley & Sons, Ltd, 24(5)

Astuti, A. (2016) Tiga Faktor Penggunaan Obat Herbal Hipertensi di Kota Jambi, Jurnal Endurance, 1(2), hal. 81–87.

Classic, N. (2014) Analisis pengaruh persepsi kualitas, keamanan dan kemanfaatan pada kepuasan dan loyalitas konsumen “Tolak Angin”, Tesis. Universitas Gadjah Mada.

Dinkes Jateng (2013) Riset Kesehatan Dasar Jawa Tengah 2013. Jakarta: Lembaga Penerbitan Badan Penelitian dan Pengembangan Kesehatan Kementerian Kesehatan RI.

Harjanti, K., Hertiani, T. dan Sumarni, S. (2014) Hubungan Pengetahuan, Persepsi kualitas dan Niat Apoteker Untuk Merekomendasikan Fitofarmaka, Jurnal Manajemen Dan Pelayanan Farmasi (Journal of Management and Pharmacy Practice), 4(3), hal. 141–145.

Hussaana, A. et al. (2016) Formula Jamu Antihipertensi and captopril are equally effective in patients with hypertension, Universa Medicina, 35(2), hal. 81–88.

Ismail, A. dan Ahmad, W. A. N. W. (2017) Autonomic receptors and nitric-oxide involvements in mediating vasorelaxation effect induced by Syzygium polyanthum leaves extract, Pharmacognosy Research, 9, hal. S9–S41.

Ismarani (2013) Kajian Persepsi Konsumen Terhadap Penggunaan Obat Herbal (Kasus di UNISMA Bekasi), Jurnal Agribisnis dan Pengembangan Wilayah, 4(2), hal. 52–63.

James, P., Oparil, S. dan Carter, B. (2014) Evidence-Based Guideline for the Management of High Blood Pressure in Adults: Report from the Panel Members Appointed to the Eighth Joint National Committee (JNC 8), JAMA, 311(5), hal. 507–520.

Jang, S. et al. (2017) Characteristics of Herbal Medicine Users and Adverse Events Experienced in South Korea: A Survey Study, Evidence-Based Complementary and Alternative Medicine. Hindawi, 2017, hal. 1–9.

Kemenkes RI (2013) Riset Kesehatan Dasar 2013. Jakarta: Lembaga Penerbitan Badan Penelitian Dan Pengembangan Kesehatan Kementerian Kesehatan Republik Indonesia.

Landazuri, P., Chamoro, N. L. dan Cortez, B. R. (2017) Medicinal Plants Used in the Management Hypertension, Journal of Analytical & Pharmeceutical Research, 5(2), hal. 1–3.

Leach, M. J. et al. (2017) Characteristics of herbal medicine users among internal medicine patients: A cross-sectional analysis, Journal of Herbal Medicine, 10, hal. 59–63.

Liwa, A. et al. (2017) Herbal and Alternative Medicine Use in Tanzanian Adults Admitted with Hypertension-Related Diseases: A Mixed-Methods Study, International Journal of Hypertension. Hindawi, 2017, hal. 1–9.

Mans, D. R. A., Grant, A. dan Pinas, N. (2017) Plant-based ethnopharmacological remedies for hypertension in Suriname–How efficacious are they?, Herbal medicine, hal. 151–188.

Nuhu, A. et al. (2018) Perception Of Herbal Medicine Practice Among Students Of Tertiary Institutions In Northern, Nigeria, FUW Trends in Science & Technology Journal, 3(2B), hal. 708–711.

Nurfaradilla, S. A., Saputri, F. C. dan Harahap, Y. (2019) Effects of Hibiscus Sabdariffa Calyces Aqueous Extract on the Antihypertensive Potency of Captopril in the Two-Kidney-One-Clip Rat Hypertension Model, Evidence-based Complementary and Alternative Medicine. Hindawi Limited, 2019.

Nurhayati dan Widowati, L. (2016) Herbal therapy and quality of life in hypertension patients at health facilities providing complementary therapy, Health Science Journal of Indonesia. National Institute of Health Research and Development, Indonesian Ministry of Health, 7(1), hal. 32–36.

Nworu, C. S. et al. (2015) Perception, usage and knowledge of herbal medicines by students and academic staff of University of Nigeria: A survey Chukwuemeka, European Journal of Integrative Medicine, 7, hal. 218–227.

Othman, C. N. dan Farooqui, M. (2015) Traditional and Complementary Medicine, Procedia - Social and Behavioral Sciences. Elsevier, 170, hal. 262–271.

Paramita, S. et al. (2018) Comparison of Adherence to the Use of Herbal Medicine with Conventional Medicine in Hypertensive Patients at Lempake Public Health Center, Samarinda City, Health Science Journal of Indonesia, 9(2), hal. 82–86.

Rumiyati, R. et al. (2016) ANTIHYPERTENSIVE TESTING OF COMBINATION OF Apium graveolans L., Orthosiphon stamineus Benth., AND Morinda citrifoliaL EXTRACT. ON NORMOTENSIVE AND HYPERTENSIVE SPRAGUE DAWLEY RATS, Majalah Obat Tradisional (Traditional Medicine Journal), 21(3), hal. 149–156.

Sekhri, K., Bhanwra, S. dan Nandha, R. (2017) Herbal products: a survey of students’ perception and knowledge about their medicinal use, International Journal of Basic & Clinical Pharmacology, 2(1), hal. 71–76.

Siska, S. et al. (2018) Effect of Apium graveolens Extract Administration on the Pharmacokinetics of Captopril in the Plasma of Rats, Scientia Pharmaceutica. Multidisciplinary Digital Publishing Institute, 86(1), hal. 6.

Triyono, A., Zulkarnain, Z. dan Mana, T. A. (2018) Studi klinis ramuan jamu antihipertensi pada pasien hipertensi derajat I, Jurnal Kefarmasian Indonesia, 8(1), hal. 17–25.

Tulunay, M. et al. (2015) Herbal medicine use among patients with chronic diseases., Journal of intercultural ethnopharmacology. SAGEYA, 4(3), hal. 217–20.

Walton, R. J., Whitten, D. L. dan Hawrelak, J. (2016) The efficacy of Hibiscus sabdariffa (rosella) in essential hypertension: A systematic review of clinical trials, Australian Journal of Herbal Medicine. National Herbalists Association of Australia, 28(2), hal. 48–51

WHO (2015) Cardiovascular diseases (CVDs). World Health Organization. Tersedia pada: http://www.who.int/en/news-room/fact-sheets/detail/cardiovascular-diseases-(cvds) (Diakses: 25 Maret 2018).

Yogiantoro, M. (2006) Hipertensi Esensial. 4 ed, in. Pusat Penerbitan Ilmu Penyakit Dalam FK UI.